Prof. Dr. med.
Michael Müller

2018 – 2020

Leitender Oberarzt für Orthopädie am Campus Virchow-Klinikum im Centrum für Muskuloskeletale Chirurgie, Charité

2021 – 2022

Sportklinik Erfurt mit dem Schwerpunkt Endoprothetik und Gelenkerhaltende Chirurgie

seit 10/2022

Departmentleiter Orthopädie und Endoprothetik am Zentralklinikum Bad Berka

12/2020

Außerplanmäßige Professur Charité – Universitätsmedizin Berlin – Für hervorragende Leistungen in Forschung und Lehre

11/2014

Habilitation zum Thema „Der Einfluss unterschiedlicher Zugangswege in der primären Hüftendoprothetik auf die Hüftmuskulatur – Funktionelle Auswirkungen und bildmorphologische Analysen“

05/2012

Facharzt für Orthopädie und Unfallchirurgie

06/2006

Promotion zum Thema „Hochauflösende MRT bei 3,0 T im Vergleich zu 1,5 T am Beispiel der Hirnstammregion.“ mit – magna cum laude –

11/2005

Erteilung der Approbation als Arzt in Berlin

04/1999 – 10/2005

Studium der Humanmedizin an der Medizinischen Fakultät (Charité), Humboldt-Universität zu Berlin

seit 10 / 2022

Departmentleiter Orthopädie und Endoprothetik am Zentralklinikum Bad Berka

2021 – 2022

Sportklinik Erfurt mit dem Schwerpunkt Endoprothetik und Gelenkerhaltende Chirurgie

2018 – 2020

Leitender Oberarzt für Orthopädie am Campus Virchow-Klinikum im Centrum für Muskuloskeletale Chirurgie, Charité– Universitätsmedizin Berlin

2013 – 2018

Oberarzt im Centrum für Muskuloskeletale Chirurgie, Charité – Universitätsmedizin Berlin

2013 – 2015

Sektionsleiter mit Schwerpunkt Endoprothetik, Gelenkerhaltende Extremitätenchirurgie
Seit 06/2015 Sektionsleiter mit Schwerpunkt Revisionsendoprothetik und septische Chirurgie

2012

Facharzt im Centrum für Muskuloskeletale Chirurgie, Klinik für Orthopädie, Klinik für Unfall- und Wiederherstellungschirurgie Charité – Universitätsmedizin Berlin

2011

Assistenzarzt (in Rotation) in der Klinik für Orthopädie, Sportmedizin und Rehabilitation am Krankenhaus Märkisch Oderland, Wriezen

2005 – 2011

Assistenzarzt im Centrum für Muskuloskeletale Chirurgie, Klinik für Orthopädie, Klinik für Unfall- und Wiederherstellungschirurgie Charité – Universitätsmedizin Berlin

2015 – 2022

Präsentation von wissenschaftlichen Ergebnissen auf nationalen und internationalen Kongressen und Symposien durch mehr als 150 Vorträge

2010 – 2022

nationale und internationale Referententätigkeit zur fachspezifischen Fort- und Weiterbildung

12/2010

Wissenschaftspreis der Arbeitsgemeinschaft für Endoprothetik (AE) für die Publikation „The association between the sagittal femoral stem alignment and the resulting femoral head centre in total hip arthroplasty.“

10/2015

Themistocles-Gluck Preis für Endoprothetik der DGOOC für die Publikation „The sagittal stem alignment and the stem version clearly influence the impingement-free range of motion in total hip arthroplasty: a computer model-based analysis.”

04/2016

Vortragspreis der Vereinigung Süddeutscher Orthopäden und Unfallchirurgen auf der Jahrestagung 2016 in Baden-Baden für den besten Vortrag mit dem Thema „Aktuelle Klassifikation und Therapiestrategien azetabulärer Defekte in der Hüftrevisionsendoprothetik“

• Deutsche Gesellschaft für Orthopädie und Orthopädische Chirurgie (DGOOC)
• Deutsche Gesellschaft für Endoprothetik (AE)
• Verband leitender Orthopäden und Unfallchirurgen (VLOU)

• spezielle orthopädische Chirurgie
• spezielle Unfallchirurgie
• Fachkunde im Strahlenschutz
• ATLS-Provider

Publikationen als Erst-/Letztautor

• Müller M, Kahl U, von Roth P, Hube R. Intraoperative Fractures of the Tibia and Femur in Knee Revision Surgery [Article in English, German]. Z Orthop Unfall . 2021 Sep 8. doi: 10.1055/a-1542-9192.
• Kienzle A, Walter S, Palmowski Y, Kirschbaum S, Biedermann L , von Roth P, Perka C, Müller M. Influence of Gender on Occurrence of Aseptic Loosening and Recurrent PJI after Revision Total Knee Arthroplasty. Osteology 2021, 1(2), 92-104; https://doi.org/10.3390/osteology1020010
• Müller M, Stöckle U, Trampuz A, Felix S, Kramer A, Wassilew G. Coronavirus Pandemic – SARS-CoV-2 in Orthopedics and Trauma Surgery. Z Orthop Unfall. 2020 Nov 5. doi: 10.1055/a-1208-0182. Online ahead of print
• Kienzle A, Walter S, von Roth P, Fuchs M, Winkler T, Müller M. High Rates of Aseptic Loosening After Revision Total Knee Arthroplasty for Periprosthetic Joint Infection. JBJS  Open Access. 2020 Aug 12;5(3):e20.00026. doi: 10.2106/JBJS.OA.20.00026. eCollection Jul-Sep 2020.
• Müller M., Böttner F. Karczewski D. Janz V., Felix S. Kramer A., Wassilew G. I.  Dealing with the COVID-19 pandemic in orthopaedics: experiences and procedure in Germany. Bone Joint Open 2020;1-6:309–. 315.
• Kilgus S, Karczewski D, Passkönig C, Winkler T, Akgün D, Perka C, Müller M. Failure analysis of infection persistence after septic revision surgery: a checklist algorithm for risk factors in knee and hip arthroplasty. Arch Orthop Trauma Surg. 2020 Apr 15. doi: 10.1007/s00402-020-03444-0.
• Müller M, Rakow A, Wassilew GI, Winkler T, Perka C. Prediction of time to prosthesis implantation as a function of joint anatomy in patients with developmental dysplasia of the hip. J Orthop Surg Res. 2019 Dec 30;14(1):471. doi: 10.1186/s13018-019-1511-4
• Müller M, Winkler T, Märdian S, Trampuz A, Renz N, Perka C, Karczewski D. The worst-case scenario: treatment of periprosthetic femoral fracture with coexistent periprosthetic infection-a prospective and consecutive clinical study. Arch Orthop Trauma Surg. 2019 Aug 20. doi: 10.1007/s00402-019-03263-y. [Epub ahead of print]
• Hipfl C, Winkler T, Janz V, Perka C, Müller M. Management of Chronically Infected Total Knee Arthroplasty With Severe Bone Loss Using Static Spacers With Intramedullary Rods. J Arthroplasty. 2019 Mar 29. pii: S0883-5403(19)30309-2. doi: 10.1016/j.arth.2019.03.053.
• Karczewski D, Winkler T, Renz N, Trampuz A, Lieb E, Perka C, Müller M. A standardized interdisciplinary algorithm for the treatment of prosthetic joint infections OUTCOME IN A CENTRALIZED AND SPECIALIZED DEPARTMENT. Bone Joint J. 2019 doi:10.1302/0301-620X.101B2
• Karczewski D, Winkler T, Perka C, Müller M. The Preoperative Microbial Detection is No Prerequisite for the Indication of Septic Revision in Cases of Suspected Periprosthetic Joint Infection.  Biomed Res Int. 2018 Jun 21;2018:1729605. doi: 10.1155/2018/1729605. eCollection 2018.
• Janz V, Wassilew GI, Perka C, Müller M. Cerclages after Femoral Osteotomy Are at Risk for Bacterial Colonization during Two-Stage Septic Total Hip Arthroplasty Revision. J Bone Jt Infect. 2018 Jul 6;3(3):138-142. doi: 10.7150/jbji.24819.
• Müller M, Trampuz A, Winkler T, Perka C. The Economic Challenge of Centralised Treatment of Patients with Periprosthetic Infections.  Z Orthop Unfall. 2018 Feb 7. doi: 10.1055/s-0044-100732.
• Fuchs M, Sass FA, Dietze S, Krämer M, Perka C, Müller M. Cemented Hemiarthroplasties Are Associated with a Higher Mortality Rate after Femoral Neck Fractures in Elderly Patients. Acta Chir Orthop Traumatol Cech. 2017;84(5):341-346.
• Feihl S, Renz N, Schütz M, Müller M. Antibiotic strategies in trauma surgery : Treatment of implant-associated infections. Unfallchirurg. 2017 Jun;120(6):486-493.
• Wilck A, Müller M. Korrekturosteotomien bei Hüftdysplasie – Pfannenschwenk. Physiopraxis 2017; 15(04): 30-33 DOI: 10.1055/s-0043-101658
• Sitterlee F, Kirschbaum S, Perka C, Müller M. [Surgical hip dislocation : Current status in the treatment of femoral acetabular impingement]. Orthopade. 2017 Feb 8. doi: 10.1007/s00132-017-3394-6. [Epub ahead of print] German
• Wassilew GI, Janz V, Perka C, Müller M. [Treatment of acetabular defects with the trabecular metal revision system]. Orthopade. 2017 Jan 12. doi: 10.1007/s00132-016-3381-3
• Kirschbaum SM, Sitterlee F, Perka C, Müller M. [Mini-open Approach Shows Good Results in Treatment of Femoroacetabular Impingement]. Z Orthop Unfall. 2017 Jan 12. doi: 10.1055/s-0042-118886.
• Müller M, Abdel MP, Wassilew GI, Duda G, Perka C. Do post-operative changes of neck-shaft angle and femoral component anteversion have an effect on clinical outcome following uncemented total hip arthroplasty? Bone Joint J. 2015 Dec;97-B(12):1615-22. doi: 10.1302/0301-620X.97B12.34654.
• Müller M, Duda G, Perka C, Tohtz S. The sagittal stem alignment and the stem version clearly influence the impingement-free range of motion in total hip arthroplasty: a computer model-based analysis. Int Orthop. 2015 Jul 2. PMID: 26130287.
• Müller M, Wassilew G, Perka C. [Diagnosis and therapy of particle disease in total hip arthroplasty]. Z Orthop Unfall. 2015 Apr;153(2):213-29. doi: 10.1055/s-0035-1545827
• Müller M, Matziolis G, Falk R, Hommel H. The bicompartmental knee joint prosthesis Journey Deuce: failure analysis and optimization strategies. Orthopade. 2012 Nov;41(11):894-904. doi: 10.1007/s00132-012-1963-2.
• Müller M, Schwachmeyer V, Tohtz S, Taylor WR, Duda GN, Perka C, Heller MO. The direct lateral approach: impact on gait patterns, foot progression angle and pain in comparison with a minimally invasive anterolateral approach. Arch Orthop Trauma Surg. 2012 May;132(5):725-31. doi: 10.1007/s00402-012-1467-x.
• Müller M, Tohtz S, Dewey M, Springer I, Perka C. Muscle trauma in primary total hip arthroplasty depending on age, BMI, and surgical approach: minimally invasive anterolateral versus modified direct lateral approach. Orthopade. 2011 Mar;40(3):217-23. doi: 10.1007/s00132-010-1730-1.
• Müller M, Tohtz S, Dewey M, Springer I, Perka C. Age-related appearance of muscle trauma in primary total hip arthroplasty and the benefit of a minimally invasive approach for patients older than 70 years. Int Orthop. 2011 Feb;35(2):165-71. doi: 10.1007/s00264-010-1166-6.
• Müller M, Crucius D, Perka C, Tohtz S. The association between the sagittal femoral stem alignment and the resulting femoral head centre in total hip arthroplasty. Int Orthop. 2011 Jul;35(7):981-7. doi: 10.1007/s00264-010-1047-z.
• Müller M, Dewey M, Springer I, Perka C, Tohtz S. Relationship between cup position and obturator externus muscle in total hip arthroplasty. J Orthop Surg Res. 2010 Jul 21;5:44. doi: 10.1186/1749-799X-5-44.
• Müller M, Tohtz S, Springer I, Dewey M, Perka C. Randomized controlled trial of abductor muscle damage in relation to the surgical approach for primary total hip replacement: minimally invasive anterolateral versus modified direct lateral approach. Arch Orthop Trauma Surg. 2011 Feb;131(2):179-89. doi: 10.1007/s00402-010-1117-0.
• Müller M, Tohtz S, Dewey M, Springer I, Perka C. Evidence of reduced muscle trauma through a minimally invasive anterolateral approach by means of MRI. Clin Orthop Relat Res. 2010 Dec;468(12):3192-200. doi: 10.1007/s11999-010-1378-5.
• Müller M, Tohtz S, Winkler T, Dewey M, Springer I, Perka C. MRI findings of gluteus minimus muscle damage in primary total hip arthroplasty and the influence on clinical outcome. Arch Orthop Trauma Surg. 2010 Jul;130(7):927-35. doi: 10.1007/s00402-010-1085-4.
• Müller M, Kääb M, Tohtz S, Haas NP, Perka C. Periprosthetic femoral fractures: outcome after treatment with LISS internal fixation or stem replacement in 36 patients. Acta Orthop Belg. 2009 Dec;75(6):776-83.
• Müller M, Morawietz L, Hasart O, Strube P, Perka C, Tohtz S. Histopathological diagnosis of periprosthetic joint infection following total hip arthroplasty: use of a standardized classification system of the periprosthetic interface membrane. Orthopade. 2009 Nov;38(11):1087-96. doi: 10.1007/s00132-009-1471-1. German.
• Müller M, Morawietz L, Hasart O, Strube P, Perka C, Tohtz S. Diagnosis of periprosthetic infection following total hip arthroplasty–evaluation of the diagnostic values of pre- and intraoperative parameters and the associated strategy to preoperatively select patients with a high probability of joint infection. J Orthop Surg Res. 2008 Jul 21;3:31. doi: 10.1186/1749-799X-3-31.
• Müller M, Disch AC, Zabel N, Haas NP, Schaser KD. Initial intramuscular perfusion pressure predicts early skeletal muscle function following isolated tibial fractures. J Orthop Surg Res. 2008 Apr 17;3:14. doi: 10.1186/1749-799X-3-14.

Fallberichte

• Tkhilaishvili T, Winkler T, Müller M, Perka C, Trampuz A. Bacteriophages as adjuvant to antibiotics for the treatment of periprosthetic joint infection caused by multidrug-resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2019 Sep 16. pii: AAC.00924-19. doi: 10.1128/AAC.00924-19.
• Müller M, Perka C, Tohtz S. Obturator externus impingement after total hip replacement. Orthopade. 2009 Nov;38(11):1113-6. doi: 10.1007/s00132-009-1469-8.

Publikationen als Coautor

• Hipfl C, Carganico T, Leopold V, Perka C, Müller M, Hardt S. Two-Stage Revision Total Hip Arthroplasty Without Spacer Placement: A Viable Option to Manage Infection in Patients With Severe Bone Loss or Abductor Deficiency.  J Arthroplasty. 2021 Jul;36(7):2575-2585. doi: 10.1016/j.arth.2021.02.040. Epub 2021 Feb 18. PMID: 33750632
• Karczewski D, Pumberger M, Müller M, Andronic O, Perka C, Winkler T.J Implications for diagnosis and treatment of peri-spinal implant infections from experiences in periprosthetic joint infections-a literature comparison and review. Spine Surg. 2020 Dec;6(4):800-813. doi: 10.21037/jss-20-12.
• Haffer H, Müller M, Ascherl R, Perka C, Winkler T. Diclofenac for prophylaxis of heterotopic ossification after hip arthroplasty: a systematic review. Hip Int. 2020 Dec 3:1120700020978194. doi: 10.1177/1120700020978194.
• Stoffel K, Horn T, Zagra L, Mueller M, Perka C, Eckardt H. Periprosthetic fractures of the proximal femur: beyond the Vancouver classification.  EFORT Open Rev. 2020 Aug 1;5(7):449-456. doi: 10.1302/2058-5241.5.190086. eCollection 2020 Jul
• Ruckenstuhl P, Wassilew GI, Müller M, Hipfl C, Pumberger M, Perka C,Hardt S. Hardt S.  Functional Assessment and Patient-Related Outcomes after Gluteus Maximus Flap Transfer in Patients with Severe Hip Abductor Deficiency. Journal of Clinical Medicine, 11 Jun 2020, 9(6)
• Kramer A, Külpmann R, Brunner A, Müller M, Wassilew G.  Risk assessment of mixed and displacement ventilation (LAF) during orthopedic and trauma surgery on COVID-19 patients with increased release of infectious aerosols. GMS Hyg Infect Control. 2020 May 14;15:Doc07. doi: 10.3205/dgkh000342. eCollection 2020.
• Tkhilaishvili T, Winkler T, Müller M, Perka C, Trampuz A. Bacteriophages as adjuvant to antibiotics for the treatment of periprosthetic joint infection caused by multidrug-resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2019 Sep 16. pii: AAC.00924-19. doi: 10.1128/AAC.00924-19.
• Renz N, Rakow A, Müller M, Perka C, Trampuz A. Long-term antimicrobial suppression prevents treatment failure of streptococcal periprosthetic joint infection. J Infect. 2019 Jul 13. pii: S0163-4453(19)30215-4. doi: 10.1016/j.jinf.2019.06.015.
• Akgün D, Müller M, Perka C, Winkler T. High cure rate of periprosthetic hip joint infection with multidisciplinary team approach using standardized two-stage exchange. J Orthop Surg Res. 2019 Mar 13;14(1):78. doi: 10.1186/s13018-019-1122-0.
• Akgün D, Müller M, Perka C, Winkler T. The serum level of C-reactive protein alone cannot be used for the diagnosis of prosthetic joint infections, especially in those caused by organisms of low virulence.  Bone Joint J. 2018 Nov;100-B(11):1482-1486. doi: 10.1302/0301-620X.100B11.BJJ-2018-0514.R1.
• Winkler T, Stuhlert MGW, Lieb E, Müller M, von Roth P, Preininger B, Trampuz A, Perka CF. Outcome of short versus long interval in two-stage exchange for periprosthetic joint infection: a prospective cohort study. Arch Orthop Trauma Surg. 2018 Nov 15. doi: 10.1007/s00402-018-3052-4. [Epub ahead of print] PMID: 30443674
• Akgün D, Müller M, Perka C, Winkler T. An often-unrecognized entity as cause of recurrent infection after successfully treated two-stage exchange arthroplasty: hematogenous infection.  Arch Orthop Trauma Surg. 2018 Jun 5. doi: 10.1007/s00402-018-2972-3.
• Wassilew GI, Heller MO, Janz V, Perka C, Müller M, Renner L. High prevalence of acetabular retroversion in asymptomatic adults: a 3D CT-based study. Bone Joint J. 2017 Dec;99-B(12):1584-1589. doi: 10.1302/0301-620X.99B12.37081.
• Akgün D, Müller M, Perka C, Winkler T. A positive bacterial culture during re-implantation is associated with a poor outcome in two-stage exchange arthroplasty for deep infection.Bone Joint J. 2017 Nov;99-B(11):1490-1495. doi: 10.1302/0301-620X.99B11.BJJ-2017-0243-R1.
• Pumberger M, von Roth P, Preininger B, Müller M, Perka C, Winkler T. Microstructural Changes of Tensor Fasciae Latae and Gluteus Medius Muscles Following Total Hip Arthroplasty: A Prospective Trial. Acta Chir Orthop Traumatol Cech. 2017;84(2):97-100.
• Habicher M, Balzer F, Mezger V, Niclas J, Müller M, Perka C, Krämer M, Sander M. Implementation of goal-directed fluid therapy during hip revision arthroplasty: a matched cohort study. Perioper Med (Lond). 2016 Dec 13;5:31. doi: 10.1186/s13741-016-0056-x.
• Renz N, Müller M, Perka C, Trampuz A. [Implant-associated infections – Diagnostics]. Chirurg. 2016 Oct;87(10):813-21. doi: 10.1007/s00104-016-0234-x.
• Balzer F, Habicher M, Sander M, Sterr J, Scholz S, Feldheiser A, Müller M, Perka C, Treskatsch S. Comparison of the non-invasive Nexfin® monitor with conventional methods for the measurement of arterial blood pressure in moderate risk orthopaedic surgery patients. J Int Med Res. 2016 May 2. pii: 0300060516635383
• Taylor WR, Szwedowski TD, Heller MO, Perka C, Matziolis G, Müller M, Janshen L, Duda GN. The difference between stretching and splitting muscle trauma during THA seems not to play a dominant role in influencing periprosthetic BMD changes. Clin Biomech (Bristol, Avon). 2012 Oct;27(8):813-8. doi: 10.1016/j.clinbiomech.2012.05.004.
• Szwedowski TD, Taylor WR, Heller MO, Perka C, Müller M, Duda GN. Generic rules of mechano-regulation combined with subject specific loading conditions can explain bone adaptation after THA. PLoS One. 2012;7(5):e36231. doi: 10.1371/journal.pone.0036231.
• Hartwig T, Streitparth F, Gross C, Müller M, Perka C, Putzier M, Strube P. Digital 3-dimensional analysis of the paravertebral lumbar muscles after circumferential single-level fusion. J Spinal Disord Tech. 2011 Oct;24(7):451-4. doi: 10.1097/BSD.0b013e3182055d74.
• Kornaropoulos EI, Taylor WR, Duda GN, Ehrig RM, Matziolis G, Müller M, Wassilew G, Asbach P, Perka C, Heller MO. Frontal plane alignment: an imageless method to predict the mechanical femoral-tibial angle (mFTA) based on functional determination of joint centres and axes. Gait Posture. 2010 Feb;31(2):204-8. doi: 10.1016/j.gaitpost.2009.10.006..
• Tohtz SW, Müller M, Morawietz L, Winkler T, Perka C. Validity of frozen sections for analysis of periprosthetic loosening membranes. Clin Orthop Relat Res. 2010 Mar;468(3):762-8. doi: 10.1007/s11999-009-1102-5.

Buchkapitel

• Müller M. Periprosthetic Hip Infection Treatment Through the ABMS Approach in The Anterior-Based Muscle-Sparing Approach to Total Hip Arthroplasty. Editors Jeffrey A. Geller, Brain J.  McGrory. 2022 Springer DOI: 10.1007/978-3-031-02059-9_1
• Kenanidis E, Tsiridis E, Lombardi Jr AV, Richardson AB, Müller M. Total Femoral Replacement (TFR). In: The Adult Hip – Master Case Series and Techniques, Editor: Eleftherios Tsiridis. Springer International Publishing AG, part of Springer Nature 2018. ISBN 978-3-319-64175-1
• Perka C, Müller M. Periprosthetic Infection. In: G. Bentley (ed.), European Surgical Orthopaedics and Traumatology: The EFORT Textbook, Springer-Verlag Berlin Heidelberg 2014
• Müller M, Perka C. Resection Arthroplasty of the Hip. In: G. Bentley (ed.),  European Surgical Orthopaedics and Traumatology: The EFORT Textbook, Springer-Verlag Berlin Heidelberg 2014